Survival of group A erythrocytes following bone marrow transplantation for reconstruction of lymphopenic hypogammaglobulinemia.

The survival of chromium-labeled group these isohemagglutinins are of donor A erythrocytes was measured in a patient origin; the donor has anti-A titers of who had previously received two bone 1:64 in saline and 1:256 by antihuman marrow transplants for reconstitution of globulin test as well as anti-B titers. No lymphopenic hypogammaglobulinemia. evidence of immunological destruction of The patient was of blood group A begroup A erythrocytes was found in this fore transplantation; the donor of blood patient suggesting that the immune sysgroup 0. The patient’s erythrocytes are tern of the donor may have become tolnow virtually 100% group 0. Anti-B erant of the group A substance of the titers are present; anti-A antibodies are recipient. not demonstrable. The cells producing